Variable Nanoparticle-Cell Adhesion Strength Regulates Cellular Uptake
نویسندگان
چکیده
منابع مشابه
Variable nanoparticle-cell adhesion strength regulates cellular uptake.
In receptor-mediated endocytosis, cells exercise biochemical control over the mechanics of adhesion to engulf foreign particles, featuring a variable adhesion strength. Here we present a thermodynamic model with which we elucidate that the variable adhesion strength critically governs the cellular uptake, yielding an uptake phase diagram in the space of ligand density and particle size. We iden...
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ژورنال
عنوان ژورنال: Physical Review Letters
سال: 2010
ISSN: 0031-9007,1079-7114
DOI: 10.1103/physrevlett.105.138101